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Did you know that they are working on a once-per-day Tramadol?
Labopharm receives FDA response to appeal of Approvable Letter for once-daily tramadol … Labopharm Inc. (TSX: DDS; NASDAQ: DDSS) today announced that it has received a written response from the U.S. Food and Drug Administration (FDA) regarding its appeal of the Agency's Approvable Letter for its once-daily tramadol formulation through the Formal Dispute Resolution process …[ Labopharm Press Release]
Labopharm's Tramadol Appeal Denied … Drug developer Labopharm Inc. said Wednesday the Food and Drug Administration will not overturn a previous decision to deny approval for the company's once-a-day version of the pain drug tramadol …[ AP/Yahoo ]
See Also:
Medline Plus Patient literature regarding Tramadol
(Medline plus is a service of the U.S. National Library of Medicine and the National Institutes of Health so it is very reliable)
Pharmacology Of Tramadol … recommended daily dose of tramadol is between 50 and 100mg every 4 to 6 hours, with a maximum dose of 400 mg/day; the duration of the analgesic effect after a single oral dose of tramadol 100mg is about 6 hours. Adverse effects, and nausea in particular, are dose-dependent and therefore considerably more likely to appear if the loading dose is high … [ Information harvested from the National Institutes Of Health scientific literature database known as Medline]
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