Authenticity Matters: How to Buy Levitra Online
When you buy Levitra online, expect to pay $25.00 or more per pill in order to get authentic, FDA-approved Levitra. Yes, the cost of Levitra will be more, but it is always better to purchase the brand-name medications than the fake, illegal “Generic” Levitra pills you will find online. There have been many studies done in which fake pills were analyzed and the ingredients in the pills were very harmful to a person’s health. It’s not worth risking your health to save a few bucks. Certainly, there are many things to consider besides the cost of Levitra when you buy Levitra online.
There are lots of people trying to rip you off when you order Levitra online. For instance, you may order Levitra 10mg, but they sell you 20mg tablets broken in half. You get a little baggie of half-tablets and Levitra crumbs.
The best way to find a legitimate Levitra merchant is to go by word of mouth. Another technique is to visit the site and test out the customer service telephone number or customer service instant message chat.
Ask them a few questions such as:
- "When I buy the Levitra, where is it shipped from"
- "What is the expiration date?"
- "How long have you been in business?"
- "How long will it take for my pills to get here"
If they do not answer the customer service number, of they take too long to respond to your questions, go to a different site. Be vigilant when you buy Levitra online. There are plenty of scam artists, and many websites sell Levitra at inflated prices. It should be in the neighborhood of what you pay at your local pharmacy, perhaps a few dollars more per pill.
Who does this site recommend?
If you are looking for brand-name Levitra manufactured by Bayer Pharmaceuticals, without a prescription in hand, I recommend AccessRx.com. They have been in business since 1999. They are located in the USA in Tempe Arizona. They offer overnight shipping.
They have a 24 hour telephone number for customer service. They even have licensed physicians and pharmacists on staff to answer your medical questions. These same doctors will review your medical and health questionnaire and decide whether to write you a prescription for Levitra.
Their prices are higher than the generics but you are assured of getting brand-name, American, FDA-Approved Levitra delivered to your door in a couple of days without having to go to a doctor. If you want to take the guess work out of things when you buy Levitra online, AccessRx is a trusted website that has been around for 14 years.
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Levitra (Vardenafil)
is a member of a family of drugs called PDE5 Inhibitors.
Levitra Dose, Levitra Cost
Levitra is available in tablet form in the following strengths: 2.5mg, 5mg, 10mg and 20mg. The cost of Levitra at a legitimate internet pharmacy is more than $25.00 per 10mg pill (the usual starting dose) when you buy 30 pills.
Maximum Dose Of Levitra
The maximum dose of Levitra is one pill per day. The usual starting dose of Levitra is 10mg once per day (60 minutes prior to sexual activity). The dose can be titrated up to 20mg or down to 2.5mg based on efficacy and side effects. Levitra can be taken without regard to food.
How Does Levitra Work
(Levitra Mechanism Of Action)
When an erection goes flaccid, you have PDE5 to thank.
Specialized penis tissue secretes a substance called cyclic guanosine monophosphate (cGMP) in response to sexual stimulation. The more cGMP available, the more durable the erection. Levitra inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability.
Levitra Pharmacokinetics; Absorption, Onset, Bioavailability:
Levitra
is rapidly absorbed from the bloodstream. It is about 15% bioavailable. Levitra (vardenafil) is about 95% bound to plasma protein. Maximum plasma concentration of Levitra occurs between 30 minutes and 2 hours after you take the pill.
The Levitra label states that you should take a pill approximately 60 minutes before sexual activity.
Levitra Pharmacodymanics, Side Effects, Metabolism
Levitra
is mostly metabolized in the liver by an enzyme known as CYP3A4 and to a lesser extent CYPC2. Levitra breakdown products are excreted in the feces (91-95%) and in the urine (2-6%).
If you are going to take Levitra, it is very important that your doctor be aware if you have a liver condition (such as cirrhosis) because you may need a special dosage adjustment.
If you try to obtain Levitra on the internet, please make sure that the person authorizing your prescription knows the true status of your liver function.
Levitra Marketing:
When Levitra was launched, they tried to create a tough guy, macho image for Levitra, as if to say that "even big strong men experience difficulty getting and staying erect".
The ads were very "in your face".
The Levitra marketers used Mike Ditka, a chubby, aging, macho, football player as a spokesman. They ran a promotion whereby you could visit the Levitra website and sign up to win tickets to the Superbowl (something that had never been done with a drug before).
However, the macho man campaign didn't work so well, so they dumped Ditka. Then they switched to a 40-something year old brunette woman who says something like : " Do you want to know little secret? Then she tells you all about how great Levitra is".
Later, Levitra advertisements focused on a more subtle effect. They differentiated it by releasing information regarding its effectiveness in people with diabetes, hypertension and other ailments common to middle aged men.
The Levitra advertisements and promotional materials used a candle as a metaphor for intimacy and passion.
These days, Levitra, which controls about 10 percent of the erectile dysfunction market, does not advertise on television.
The BIG Discovery
Some very smart scientists discovered that cyclic guanosine monophosphate (cGMP) was the key to sustaining an erection.
They discovered that when a man gets sexually stimulated, a chain reaction occurs in the tissue of the penis that results in elevated levels of a substance called cyclic guanosine monophosphate (cGMP).
As long as there are sufficient levels of cGMP, the penis can remain erect. The more cGMP, the more robust and durable the erection.
If you inhibit the degradation of cGMP it stays around in the penis longer, producing a more durable erection.
Another way you can think of Levitra (and all other similar medicines) is that it preserves the elevated levels of cGMP that are created when a man is sexually stimulated for a stronger, more lasting erection.
That's how Levitra works - Levitra blocks the enzyme phosphodiesterase-5 (PDE5) which is responsible for the neutralization of cGMP. Levitra (Vardenafil) is a highly selective inhibitor of PDE5. (PDE5 is not the only phosphodiesterase involved in the erectile physiology but it appears to be the most important one).
The nice thing about PDE5 blockers is that they shouldn't cause erections at inappropriate times because they only block degradation of cGMP produced in reaction to sexual stimulation, such as thinking about something sexy. If you are not being sexually stimulated, there is no cGMP to protect, so the drug remains in the background.
Levitra Information On The Internet:
Recent Scientific Trial Regarding Levitra (vardenafil) versus Cialis (tadalafil) & Viagra (Sildenafil)
regarding effects on pulmonary smooth muscle tissue (in an animal model).
Vardenafil, but not sildenafil or tadalafil, has calcium-channel blocking activity in rabbit isolated pulmonary artery and human washed platelets.... Sildenafil and tadalafil did not affect the phenylephrine-induced contractions, whereas vardenafil reduced the maximal responses … results indicate that vardenafil, in contrast to sildenafil or tadalafil, also blocked Ca(2+) fluxes, thus enhancing its vasorelaxation of the pulmonary artery …[British Journal of Pharmacology (2008) 154, 787-796; doi:10.1038/bjp.2008.141; published online 21 April 2008]
Levitra Price Comparison: There is a lot of competition between sites that sell Levitra. This competition drives down the prices.
Our editors have searched the Internet to find helpful information about Levitra. Following are several websites that will allow you to learn more about this erectile dysfunction medication.
Also, make sure your cost of Levitra is reasonable when you buy Levitra online. See our list of top websites that sell this medication and compare prices to get the best deal for online Levitra.
Levitra Versus Viagra From Forbes magazine 10/06/03; by M. Herper and A. Lagorce; Side by side comparison of various characteristics; cost, pharmacokinetics, spokesperson, marketing, etc.
Levitra.com Geared to patients; all about Levitra and erections, including an illustrated picture of how an erection works; also contains information on what to expect once you take the pill.
Official Levitra Prescribing Information (Package Insert); dose, mechanism of action, side effects, precautions, warnings; patient information; very technical, don't get scared when you come to the section on warnings and side effects. [ This information is provided as a PDF document. You will need Adobe Acrobat to view this information]
Levitra Patient Information Who should take Levitra, who should avoid Levitra, drug interactions, warnings, cautions, drug interactions.
Levitra Scientific Papers ( from the National Library of medicine) automated Medline search; a listing of scientific papers in abstract form regarding Levitra.
Levitra News (from Google) ; recently published news regarding Levitra.
